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What is Tesamorelin?

Tesamorelin is a synthetic 44 amino acid polypeptide analogue of growth hormone releasing hormone (GHRH). It is in a class of medications called human growth hormone-releasing factor (GRF) analogs. It works by increasing the production of a certain natural substance that can decrease the amount of body fat.

Tesamorelin is used to decrease the amount of extra fat in the stomach area in adults with human immunodeficiency virus (HIV) who have lipodystrophy (increased body fat in certain areas of the body).

Tesamorelin is given subcutaneously and has major effects on glucose and lipid metabolism, but has not been linked to serum aminotransferase elevations during therapy or to instances of clinically apparent acute liver injury.

Tesamorelin activates GHRH receptors in the pituitary which leads to synthesis and release of growth hormone that acts on multiple cells of the body including hepatocytes where it stimulates production of insulin like growth factor-1 (IGF-1).

Tesamorelin Benefits

• Burning fat. A number of studies have found that tesamorelin can significantly reduce fat in the stomach, in muscles, and even in the liver.
• Increasing HGH. Several studies have noted that tesamorelin increases HGH in test subjects. This may have an impact on the body’s ability to grow and repair tissue.
• Reducing the risk of cardiac disease. Preliminary research suggests that tesamorelin may reduce the risk of cardiovascular diseases.
• Increased muscle. In elderly test subjects, tesamorelin has been shown to increase strength, muscle density, and the size of muscles.
• Nerve tissue repair.
• Improving cognition. Research has shown that tesamorelin can actually help test subjects with mild cognitive impairment perform better on cognitive tests.

Tesamorelin Analysis report

Tesamorelin uses

Tesamorelin was evaluated and found to be effective in decreasing visceral adiposity in patients with lipodystrophy associated with antiretroviral therapy of human immunodeficiency virus (HIV) infection.

Tesamorelin is also being evaluated as therapy of insulin resistance, obesity and nonalcoholic fatty liver.

How tesamorelin given? Reconstitute Tesamorelin

Wash your hands with soap and water before using this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.

Inject this medication under the skin on your stomach (abdomen) as directed by your doctor, usually once daily. To help you remember, use it at the same time each day.

Pick an injection site that is below your belly button to the left or right. Avoid any area with scar tissue, bruises, reddening, or irritation.

Before injecting each dose, clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin.

Tesamorelin side effects

Less serious side effects may include: night sweats; muscle spasm; nausea, vomiting, upset stomach; pain, redness, itching, swelling, bruising, bleeding, or other irritation where the injection was given; mild rash or itching; depressed mood, sleep problems (insomnia).

Stop using tesamorelin and call your doctor at once if you have a serious side effect such as: pain in your arms or legs; numbness or tingling in your hands or fingers; pounding heartbeats or fluttering in your chest; high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss); wrist pain or numbness; swelling in your hands, ankles, or feet; pain or stiffness in your muscles or joints;

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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