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What is MGF?

Mechano Growth Factor, or MGF, is a peptide derived from a different sequence of insulin-like growth factor-1 (IGF-1). It is also called IGF-1Ec, has a unique E domain with a 49bp insert in humans (52bp in rodents; IGF-1Eb), which results in a reading frame shift during the IGF-1 gene splicing to produce a distinct mature isoform.

We have studied the effects of the MGF-24aa-E peptide on proliferation and differentiation of primary human muscle cell cultures isolated from healthy subjects of different ages.

We found that MGF-E peptide significantly increases the proliferative life span and delays senescence of satellite cells isolated from neonatal and young adult but not from old adult muscle, hypertrophy associated with a significant decrease in the percentage of reserve cells was observed in all cultures.

It is concluded that the MGF-24aa-E peptide alone has a marked ability to enhance satellite cell activation, proliferation and fusion for muscle repair and maintenance and could provide a new strategy to combat age related sarcopenia without the oncogenic side effects observed for IGF1.

MGF peptide bodybuilding

MGF has the ability to encourage repair and growth of wasted tissue through the activation of muscle stem cells, thereby increasing the synthesis of proteins necessary for tissue growth. This peptide is ideal for anyone suffering from muscle loss, either due to old age or a particular condition.

Test report

MGF uses

MGF is mainly used in conditions requiring anabolic enhancement, including bony and soft tissue repair following injury, sarcopenia, stroke, or heart attack.

MGF peptide is especially beneficial for individuals requiring enhanced recovery and muscle building following eccentric muscle loading.

MGF is most commonly combined with IGF1 LR3 because it affects both insulin-like growth factor 1 and mechano growth factor, generating the maximum muscle gain in the combination.

MGF peptide benefits

Essential for recovery, repair, and growth of new cells
Triggers fusion of ‘satellite’ stems cells to the muscle fibers.
Activates muscle satellite stem cells
Satellite cells provide additional nuclei required for repair

MGF Dosage:

MGF has an effect similar to IGF – 1, many users inject between 100 and 200mcg each of the trained muscle groups.

The most effective method was to inject subcutaneously 2 times a week, at best on non-training days, at a regular interval of 200mcg for four weeks.