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Anabolic steroid, also called anabolic-androgenic steroid, drug that mimics the male hormone testosterone in its ability to increase the growth of muscle tissue and in its promotion of male secondary sex characteristics. Some examples of anabolic steroids are testosterone, nandrolone, stanozolol, oxandrolone, trenbolone and oxymetholone etc.
Anabolic steroids target the androgen receptor, the natural biological receptor for testosterone and its metabolite dihydrotestosterone. Stimulation of the androgen receptor results in cell growth, leading to an increase in muscle size. It also leads to virilization—the development of masculine traits, including increased libido and deepening of the voice.
Anabolic steroids are commonly abused by human athletes to build muscle and improve strength.
The drugs are also used in livestock to augment muscle mass, and they are sometimes given to racehorses to increase stamina and heighten performance.
Anabolic steroids are used medically in humans to treat a variety of conditions, including anemia, breast cancer, hypogonadism, short stature, malnutrition, osteoporosis, and human immunodeficiency virus (HIV) wasting syndrome.
Anabolic steroids are also used in veterinary medicine (e.g., to aid recovery from starvation or injury).
Abusing anabolic steroids can cause significant damage to the body. In humans, it may lead to coronary heart disease, sexual and reproductive disorders, immunodeficiency, liver damage, developmental delay, aggressive behavior, susceptibility to connective tissue damage, and (in women) irreversible virilization.
Similar side effects can occur in livestock and other animals. In horses, for example, anabolic steroids can cause liver damage and weakened tendons, and may lead to reduced testicular size and sperm production in stallions, and altered reproductive cycles in mares. Anabolic steroids are easily detected in urine and blood.